Spray-Induced Gene Silencing (SIGS) is one of the emerging strategies for sustainable plant protection: exogenous double-stranded RNA (dsRNA) can be used to control fungal pathogens in a targeted and residue-free manner. In this context, the Institute of Fruit Growing at Geisenheim University is developing a SIGS platform with a focus on the post-harvest phase — an area of application in which key limitations of open-field applications (UV stability, application drift, biosafety) are mitigated by the controlled storage environment. We position our work as the foundation for European SIGS research, thereby paving the way for the authorisation and practical implementation of this sustainable and safe plant protection strategy.